Uses Of Synthetic Oligonucleotides
In molecular biology experiments, it is important to fabricate Oligonucleotides which is a result of DNA and RNA synthesis. These tiny bits of nucleic acids such as Poly(dA) can be produced in a laboratory through a solid phase chemical synthesis. Oligonucleotides are one of the key ingredients for DNA sequencing, artificial gene synthesis, gene library construction, polymerase chain reaction and as a molecular beacon probe.
Synthetic Oligonucleotide is commonly used to screen viral diseases. It is also used on many molecular biology experiments, most especially on identifying genes or DNA sequencing. In the process of a DNA sequencing, Oligonucleotides are used as primers for the DNA enzymes, it will serve as a pattern for the DNA enzymes to follow. Once synthesized, the DNA enzymes and Oligonucleotides will form a double strand DNA. Another great thing about Oligonucleotides is that it has been a great use for microarrays. These are used to screen genetic diseases such as breast cancer. In recent developments, Oligonucleotide microarrays such as the ViroChip can be used to detect illnesses through a person’s phlegm and other body secretions. This is extremely useful as it has become easier to determine viral infections as symptoms are often the same.
Article submitted by The Midland Certified Reagent Company. The Midland Certified Reagent Company specializes in RNA, LNA, Oligonucleotides, Polynucleotides and DNA synthesis. The company has been a leader in this field for more than 20 years and pioneered in using MALDI-TOF mass spectrometry to ensure that quality is maintained optimum.